Ductal in situ breast cancer

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August 26, , by NCI Staff. Ductal carcinoma in situ, or DCIS, is a noninvasive condition in which abnormal cells are found in the lining of a breast duct. A new study suggests that women who are diagnosed with abnormal cells in the lining of a breast duct—a noninvasive condition called ductal carcinoma in situ, or DCIS—generally have a low risk of dying from breast cancer. In addition, treating these lesions may help prevent a recurrence in the breast but does not appear to decrease the already-low risk of dying from the disease, even after 20 years of follow-up. The findings , from an observational study involving more than , women, were published August 20 in JAMA Oncology. Steven A.
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Risk of Breast Cancer Death is Low After a Diagnosis of Ductal Carcinoma in Situ

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Invasive breast cancer | Cancer Research UK

Each breast contains 15 to 20 lobes of glandular tissue, arranged like the petals of a daisy. The lobes are further divided into smaller lobules that produce milk for breast-feeding. Small tubes ducts conduct the milk to a reservoir that lies just beneath your nipple. Ductal carcinoma in situ DCIS is the presence of abnormal cells inside a milk duct in the breast.
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20 Things to Know About DCIS, or ‘Stage 0’ Breast Cancer

There is a spectrum of changes in the breast tissue from normal tissue to breast cancer; it goes something like this:. The difference between DCIS and breast cancer is seen under the microscope - a lack of invasion of the basement membrane that surrounds the ductal tissue. Since the breast cells cannot invade this tissue, they cannot leave the breast, or metastasize. This is a big difference that takes some time to understand. Thus, DCIS is treated with surgery - often lumpectomy and radiation , sometimes mastectomy, and sometimes hormonal therapy but never chemotherapy.
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Ductal carcinoma in situ DCIS , also known as intraductal carcinoma , is a pre-cancerous or non-invasive cancerous lesion of the breast. In DCIS, abnormal cells are found in the lining of one or more milk ducts in the breast. In situ means "in place" and refers to the fact that the abnormal cells have not moved out of the mammary duct and into any of the surrounding tissues in the breast "pre-cancerous" refers to the fact that it has not yet become an invasive cancer.
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